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Problem 42

A patient age 33 years with a history of unexplained mild thrombocytopenia presented as a surgical emergency‚ with central abdominal pain and vomiting. At operation a segment of bowel showed extensive intramural haemorrhage‚ and on subsequent histological examination thrombi were found in small arterial blood vessels. The composite image shows bone marrow stained by May-Grunewald-Giemsa (42.1 and 42.2) and by Perl`s stain (42.3). Urine deposit stained by Perl`s stain is illustrated in 42.4. What is the likely diagnosis and what confirmatory test(s) would you advise?



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